| Recruitment | Week 1 | Week 2 | Further samples | Convalescent samples | |||||||||||||
| Day | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | Weekly until max 100 days |
3 & 6 months after recruitment |
| >40kg | R | P | S | P | S | P | S | P | S | P | S | P | S | P | S | S | C |
| 20 to 40kg | R | P | S | P | S | P | S | P | S | P | S | P | S | P | S | S | C |
| 10 to 20kg | R | P | S | P | S | P | S | P | S | P | S | P | S | P | S | S | C |
| 4 to 10kg | R | P | S | P | S | P | P | P | S | P | P | P | S | P | P | S | C |
| <4kg | R | P | S | P | S | P | P | P | S | P | P | P | S | P | P | S | C |
| Sample priority | 1 | 11 | 2 | 11 | 5 | 11 | 7 | 11 | 3 | 11 | 8 | 11 | 10 | 11 | 9 | 6 | 4 |
Sampling pattern - In Patient Recruitment. R = recruitment samples. S = serial samples including pathogen samples; P = research pathogen samples only; C = convalescent samples (see Table 3). *Resolution of acute illness is defined in section 3.7. In the event that local resource limitations require sampling frequency to decrease, samples will be prioritised as shown (1=highest priority).