Run a MAIC analysis
You can run the latest version of MAIC by downloading our pymaic python package, or open a terminal and type:
pip install pymaic
Method
MAIC integrates data from multiple different sources by encoding a simple heuristic which is intuitive to biologists: we put a different amount of weight on information, depending on how much we believe it. One way to decide how much weight to put on an experiment is to ask whether it found similar results to other experiments. MAIC does this, deriving a weighting for each data source, by applying this formula iteratively to weight experiments against each other:
\[\begin{matrix} w_{j}^{L} = \sqrt{\frac{\sum g_{i} \in L_{j}s_{i}}{n_{j}}} \\ \end{matrix}\]Click here to read the full description of the algorithm